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 My Summer
in Medical Research
Christopher Parish Hirschi
Math-Science International Baccalaureate High School Class of
December 2005 Wichita Falls, Texas
This summer I had an unexpected chance to play an
active role in a national medical research project. I participated
in a phase III clinical research trial to determine if compressing
the time interval between chemotherapy treatments improves outcome
for child and adolescent patients with Ewing's sarcoma. Ewing's
sarcoma is a type of aggressive pediatric bone cancer that
affects 150 people in the United States each year. The majority of
victims are between the ages of 14 and 17 and experience a
period of rapid growth when the disease strikes. I participated in
this research trial via Cook Children's Medical Center in Fort
Worth, Texas, under the direction of Jeffrey R. Murray, M.D., Medical
Director of the Adolescent Oncology Program.
The trial was to
determine whether reducing the amount of time between chemotherapy
rounds by a week would improve, decrease, or have no
effect on the survival rates for Ewing's sarcoma patients. I have a
particular interest in the end result of this experiment because I have
this type of cancer. To be more specific, I am a six-month survivor
of Askin's tumor, a very rare form of Ewing's that attacks
the ribs of tall, thin, white teenage males. The clinical
trial for me consists of 14 rounds of infusions of five toxic drugs
administered every 21 days, which is the current standard inpatient
treatment protocol for Ewing's. Those in the experimental arm of the
trial received the same medications, but at two-week
intervals.
Although it is far too early to determine the
final outcome of this clinical trial, hopefully pediatric
oncologists will learn which treatment interval is more effective
for long-term survival.
Editor's Note: We at NSHSS wish
Christopher all the best and thank him for sharing his
experience.
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